High fat ketogenic diet
There are truly a plethora of avenues to go down in this area of research and there is no lack of things to research and comment on. While there was a significant decrease in the weight of obese patients who were on a ketogenic diet ( 12 ), the reverse occurred when the diet changed to one high in carbohydrates ( 14 ). Recent studies from various laboratories ( 10, 11 ), including our own ( 12 ), have shown that a high fat diet rich in polyunsaturated fatty acids (ketogenic diet) is quite effective in reducing body weight and the risk factors for various chronic diseases. Posted on Monday, February 18th, 2013 at 7:07 am. In this diet, the fat to carbohydrate ratio is 5:1. RESULTS: The weight and body mass index of the patients decreased significantly (P CONCLUSIONS: The present study shows the beneficial effects of a long-term ketogenic diet. All rights reserved This article has been cited by other articles in PMC. The ketogenic diet was originally introduced in 1920 ( 13 ). Besides, everyone is drinking the MCT koolaid these days. The NCBI web site requires JavaScript to function. Call me ignorant but I had no idea until this point that there was more than one phase to insulin secretion. Keywords: Diet, Ketosis, Obesity Obesity has become a serious chronic disease in both developing and developed countries. Changes in these parameters were monitored after eight, 16 and 24 weeks of treatment. These two work in a similar manner, acting on the beta cells to release insulin. A while ago Michael and I were discussing future article topics. The body weight, body mass index, total cholesterol, low density lipoprotein (LDL) cholesterol, high density lipoprotein (HDL) cholesterol, triglycerides, fasting blood sugar, urea and creatinine levels were determined before and after the administration of the ketogenic diet. The first phase of insulin secretion lasts approximately 10 minutes, and the second phase of insulin secretion picks up after the first and lasts for several hours. Therefore, the present study confirms that it is safe to use a ketogenic diet for a longer period of time than previously demonstrated.
While infusions of GLP-1 seem to increase the insulin release in diabetics significantly ( source ), Lewis et al. Type 2 diabetes is associated with a shift from biphasic, to monophasic insulin release, and it is therefore important to establish the cell biology of insulin release kinetics. This article delves deeper into the signaling involved in (what I learned is called) biphasic insulin secretion. Furthermore, it decreased the level of triglycerides, LDL cholesterol and blood glucose, and increased the level of HDL cholesterol. When sugar is ingested, there are two very important proteins that are released: GIP and GLP-2. But even though I have a couple of pretty cool MCT articles sitting around on my desk, I want an interesting topic. Administering a ketogenic diet for a relatively longer period of time did not produce any significant side effects in the patients. I would like to add now that GIP is also released in response to fat intake. Michael pointed me to one of his old articles on physiological insulin resistance as an idea. It significantly reduced the body weight and body mass index of the patients. The first and second phases are related, yet separate processes, it turns out. Abstract BACKGROUND: Although various studies have examined the short-term effects of a ketogenic diet in reducing weight in obese patients, its long-term effects on various physical and biochemical parameters are not known. People become monophasic in their insulin releasing, like diabetics. The conclusion we can now make in low carb dieters: a similar process is happening. WHY does blood glucose rise in response to a low carb diet. This is initiated by the influx of glucose into the beta cells of the pancreas, leading to an eventual depolarization and activation of calcium channels that regulate insulin release.
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