Low calorie diet life span
During an enrollment period that lasted from May to November 2001, 132 subjects from the Philadelphia Veterans Affairs Medical Center were randomly assigned to either the low-carbohydrate diet or the low-fat diet, with use of a preestablished algorithm generated from a random set of numbers. Future studies evaluating long-term cardiovascular outcomes are needed before a carbohydrate-restricted diet can be endorsed. Methods Subjects The study was approved by the institutional review board at the Philadelphia Veterans Affairs Medical Center, and an approved consent form was signed by each subject. Abstract Background The effects of a carbohydrate-restricted diet on weight loss and risk factors for atherosclerosis have been incompletely assessed. Methods We randomly assigned 132 severely obese subjects (including 77 blacks and 23 women) with a mean body-mass index of 43 and a high prevalence of diabetes (39 percent) or the metabolic syndrome (43 percent) to a carbohydrate-restricted (low-carbohydrate) diet or a calorie- and fat-restricted (low-fat) diet.
This finding should be interpreted with caution, given the small magnitude of overall and between-group differences in weight loss in these markedly obese subjects and the short duration of the study. Inclusion criteria were an age of at least 18 years and a body-mass index (the weight in kilograms divided by the square of the height in meters) of at least 35. Conclusions Severely obese subjects with a high prevalence of diabetes or the metabolic syndrome lost more weight during six months on a carbohydrate-restricted diet than on a calorie- and fat-restricted diet, with a relative improvement in insulin sensitivity and triglyceride levels, even after adjustment for the amount of weight lost. Article Activity 515 articles have cited this article Article The differences in health benefits between a carbohydrate-restricted diet and a calorie- and fat-restricted diet are of considerable public interest.
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Low calorie diet life span
